Image Analysis

Image Analysis

Image analysis is the process of converting digital information from images into measurements that characterize the status of each and every cell in an experiment. A digital image is basically a n-dimensional array of pixels, where each of the pixels has its own value...
Polar Distribution Score

Polar Distribution Score

When looking at the microscopy images of ER exit sites we noticed that after a certain perturbation they change the distribution around the nuclei. ER exit sites in normal cells are more concentrated on one side. After the perturbation, the ER exit sites uniformly...
Mitochondria Structure & Measurement

Mitochondria Structure & Measurement

The structure of mitochondria has been linked to disruptances in cellular processes, such as energy metabolism, calcium storage and lipid synthesis. Since mitochondria can be easily stained and imaged, it is also possible to measure their dimensions and detect whether...
Cell Painting

Cell Painting

The term “Cell painting” was first coined in 2016, by Bray et al., describing a morphological profiling assay to reveal eight broadly relevant cellular components or organelles by multiplexing six fluorescent dyes in five different channels. In addition, they designed...