Toxicity prediction from CellPainting data

Toxicity prediction from CellPainting data

In the field of chemical research, computational methods have become indispensable for predicting toxicity and exploring vast chemical spaces. There are two powerful tools that we can use to predict the toxicity of chemicals: ProTox-II and ChemProp. ProTox-II is a web...
CellPose vs. CellProfiler segmentation comparison

CellPose vs. CellProfiler segmentation comparison

Image segmentation is an essential process and one of the first challenges in analyzing images of complicated cellular phenotypes at the single cell level. Accurate and efficient segmentation is crucial for extracting meaningful information from images and analyzing...
Preprocessing Extracted Features

Preprocessing Extracted Features

Preprocessing extracted features from cell painting images is an essential step in image-based profiling because it helps to ensure that the data is of high quality and is ready for further analysis. This can help to eliminate sources of error or bias in the data,...
Image Quality Control

Image Quality Control

The verification of image quality in high throughput experiments is virtually impossible to do by hand, that is why you can use automated methods to objectively label and remove images and cells that are affected by artifacts. These strategies aim to reduce the...
Image Analysis

Image Analysis

Image analysis is the process of converting digital information from images into measurements that characterize the status of each and every cell in an experiment. A digital image is basically a n-dimensional array of pixels, where each of the pixels has its own value...
Polar Distribution Score

Polar Distribution Score

When looking at the microscopy images of ER exit sites we noticed that after a certain perturbation they change the distribution around the nuclei. ER exit sites in normal cells are more concentrated on one side. After the perturbation, the ER exit sites uniformly...